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Report predicts sharp increase in deaths from drug-resistant infections by 2050


Lack of prevention strategies and new drug development along with overuse of antibiotics are factors in the rise of antibiotic-resistant pathogens

In a forecast that threatens to unravel decades of medical progress, a new global study predicts that antibiotic-resistant infections could claim more than 39 million lives by 2050, potentially plunging the world into a post-antibiotic era.

The report, released by the Global Research on Antimicrobial Resistance (GRAM) Project, paints a picture of a looming public health crisis where once-treatable diseases may again become deadly.

A Growing Global Threat

The GRAM report, published in The Lancet and presented at a global health summit in Geneva, shows a trend: Deaths attributed to antibiotic-resistant infections are projected to increase from approximately 1.14 million in 2021 to 1.91 million in 2050.

“Antimicrobial medicines are one of the cornerstones of modern healthcare, and increasing resistance to them is a major cause for concern,” Dr. Mohsen Naghavi, study author, professor of health metrics sciences, and team leader of the AMR Research Team at the Institute of Health Metrics, University of Washington, said in a press release.

The findings highlight that AMR (antimicrobial resistance) has been a significant global health threat for decades and that this threat is growing. “Understanding how trends in AMR deaths have changed over time, and how they are likely to shift in future, is vital to make informed decisions to help save lives,” he added.

Demographic Shift in Antibiotic Resistance

The report highlights a demographic shift. While mortality rates from antibiotic-resistant infections among children under 5 have declined, older adults are increasingly contracting more superbugs. The older adult population, particularly those with multiple underlying health conditions, is at heightened risk as antibiotic efficacy wanes.

However, while seniors are anticipated to be the most affected, the problem of AMR affects everyone, Dr. Sharon Nachman, chief of the Division of Pediatric Infectious Diseases at Stony Brook Children’s Hospital, told The Epoch Times.

“It has a trickle-down effect to all of our patients,” she noted. “Don’t make the mistake that this is an elderly population issue— it’s actually not—it crosses all the ages.”

Factors Fueling the Rise of Antibiotic-Resistant Pathogens

Health authorities attribute the rise of antibiotic-resistant pathogens to several interlinked factors:

  • Overuse of antibiotics in both human and veterinary medicine
  • Inadequate infection prevention strategies
  • Lack of new drug development

Globally, many countries continue to prescribe antibiotics unnecessarily for viral infections, such as colds and flu, further exacerbating the problem.

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