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Study Shows Older Patients More Vulnerable Due to Lack of Anemia Screening


The study highlights a gap in health screening, where treatable causes of anemia such as low B12, folate, and iron are often overlooked.

Anemia is a common yet insidious condition with symptoms that are often missed or disregarded. The impact of this condition on one’s health and well-being underscores the importance of early detection through regular screening for effective management and treatment.

A study from the University of Limerick School of Medicine in Ireland, published in early 2024, revealed that physicians are not adequately screening for anemia. The retrospective cohort study, involving 112,181 adult patients aged 18 years and older, found that 12 percent of patients had anemia—higher than expected.

The study indicated that the prevalence of anemia was considerably higher in women than men until ages 55 to 59, after which it became more prevalent in men. Anemia diagnoses increased significantly with age, reaching 33.4 percent for participants over 75 years old, with the study noting that “Prevalence increased more rapidly with age in men than in women.”

Prevalence of anaemia, iron, and vitamin deficiencies in the health system in the Republic of Ireland: a retrospective cohort study Conor Cian Clancy, Leonard D Browne, Robert Gilligan, Ophelia Blake, Austin G Stack https://doi.org/10.3399/BJGPO.2023.0126 Copyright © 2024, CC BY license material.
Prevalence of anaemia, iron, and vitamin deficiencies in the health system in the Republic of Ireland: a retrospective cohort study Conor Cian Clancy, Leonard D Browne, Robert Gilligan, Ophelia Blake, Austin G Stack https://doi.org/10.3399/BJGPO.2023.0126 Copyright © 2024, CC BY license material.

The study exposed a crucial gap in health care screening: treatable causes of anemia, like low vitamin B12, folate, and iron, were often neglected and left unexamined. Less than 20 percent of anemic patients were tested for B12 and folic acid deficiencies, and only one-third of them were screened for iron deficiency at their three-month follow-up appointment.

Recent data from the National Health and Nutrition Examination Survey in the United States revealed that over 70 percent of iron-deficiency anemia cases are undetected in pregnant women and children. An article from 2022 in the American Journal of Public Health concluded that the current American guidelines on anemia screening are outdated or inconclusive.

What Is Anemia?

The Mayo Clinic defines anemia as a condition where the body lacks enough healthy red blood cells, resulting in inadequate oxygen delivery to tissues and organs. Hemoglobin, which carries oxygen to body tissues, relies on sufficient iron for production.

Various factors, including nutritional deficiencies, chronic diseases, digestive disorders, or genetics, can lead to anemia. Treatment options depend on the underlying cause and may include dietary changes, supplements, and medical interventions for more severe cases.

Types and Causes of Anemia

There are several types and causes of anemia, including:

Iron-Deficiency

The most common type, resulting from insufficient iron for hemoglobin production, often due to blood loss or inadequate dietary intake.

Vitamin Deficiency

Caused by deficiencies in essential vitamins like B12, folate, and B6, crucial for red blood cell production.

Hemolytic Anemias

Occurs when red blood cells are destroyed faster than produced, leading to a shortage of red blood cells.

Aplastic Anemia

Rare but serious, resulting from insufficient red blood cell production due to bone marrow damage.

Sickle Cell Anemia

A genetic form where red blood cells become rigid and sticky, causing vessel blockages and decreased oxygen delivery.

Chronic Diseases

Conditions like kidney disease or cancer can lead to anemia due to decreased production or increased destruction of red blood cells.

Pregnancy

Increased blood demand during pregnancy can cause anemia due to additional iron needs for fetal growth.

Bone Marrow Disorders

Disorders like leukemia affecting bone marrow can interfere with red blood cell production, leading to anemia.

Certain medications can induce anemia as a side effect. Understanding anemia in older individuals is crucial due to its impact on cognitive function, mood, cardiovascular health, among other aspects.
Research published in Blood highlighted anemia as a risk factor for cognitive decline, cardiovascular diseases, and other health complications in older adults. Recognizing symptoms of anemia like fatigue, weakness, and cognitive disturbances is vital for timely interventions and treatment for this condition.

Pale or yellowish skin, cold extremities, headaches, and cognitive issues can signal anemia. Screening for nutritional deficiencies like B12 and folate is essential in identifying potential causes of anemia.



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