The MSCI World Equity index was down 0.3 percent on the day, while Europe’s STOXX 600 eased 0.2 percent to sit just below a one-month high hit on Tuesday.
European indexes strengthened earlier in the week as investor sentiment became more positive about Ukraine peace talks. But optimism petered out after Ukrainian President Volodymyr Zelenskyy said that no quick resolution is expected and the country prepared for new Russian attacks.
The STOXX 600 was on track for a 5.8 percent drop in the first quarter of 2022, its biggest quarterly fall since it plunged 23 percent in the first three months of 2020.
U.S. stock futures pointed to a slightly more upbeat Wall Street session, but the S&P 500 was still set for its first quarterly drop in two years.
Government bonds also sold off this quarter with investors bracing for major central bank rate hikes to combat surging inflation.
A closely-watched part of the U.S. Treasury yield curve briefly inverted on Tuesday, which can be interpreted as an indicator that there will be a recession in one to two years’ time.
“There’s going to be some money coming out of equities, into fixed income, especially because equities have had quite a spectacular rebound in the last few weeks,” said Guillaume Paillat, multi-asset portfolio manager at Aviva Investors.
“The yield curve is telling us that the economy’s going to slow and effectively maybe bonds, given that they’ve sold off so much, are a bit more attractive here compared to equities,” he said, adding that he does not expect a recession and still expects markets to benefit from re-opening following COVID-19 lockdowns.
In Europe, inflation data showed record-high price rises in France in March and a 7 percent year-on-year rise in Italy, following sky-high readings from Germany and Spain a day earlier.
The sell-off in U.S. Treasuries has paused in recent days, with the 10-year yield edging lower on Thursday to 2.3197 percent, compared to a three-year high of 2.557 percent touched on Monday.
European government bond yields were also down on the day, but still the German 10-year yield was set for its biggest monthly rise since 2009.
Oil prices plunged during the Asian session and extended losses in European trading hours.
Brent crude futures were down 6 percent at $101.4, while U.S. West Texas Intermediate futures were down 5.8 percent at $106.87 at 1024 GMT.
Oil prices have surged since Russia invaded Ukraine in late February and the United States and allies responded with hefty sanctions on Russia, the second-largest exporter of crude.
The euro was down 0.6 percent at $1.1094, having been boosted earlier in the week by hopes for peace in Ukraine.
The dollar was little changed against the yen, with the pair at 121.805, having stabilized after the yen fell to its lowest since 2015 on Monday on expectations that the Bank of Japan would be markedly more dovish than the Fed.
Commodity-linked currencies such as the Norwegian crown were down.
Gold edged lower, but was still set for its biggest quarterly rise since the third quarter of 2020.
Bitcoin was little changed at around $47,249.
By Elizabeth Howcroft and Samuel Indyk