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Experts warn that a new drug called “Tranc Dope” is infiltrating the UK’s illegal drug market


Xylazine has been associated with one fatality and can cause issues such as compromised airways and skin ulcers that may result in amputations.

A recent study published in the journal Addiction has raised concerns about the introduction of a potent sedative called “tranq dope” into the illegal drug market in the UK. Researchers have identified xylazine, a non-opioid animal sedative, in 35 cases across Britain by August 2023, indicating a potential widespread use beyond current findings.

According to experts from King’s College London, combining xylazine with opioids like fentanyl or heroin poses a higher risk of mortality due to airway obstruction and can lead to skin ulcers that, if infected, may require limb amputation. Additionally, chronic use of xylazine can significantly lower breathing and heart rates, posing serious health risks.

Xylazine, commonly known as “tranq” or “tranq dope” when mixed with opioids, has infiltrated counterfeit prescription medications, including codeine, diazepam, cocaine, and THC vapes.

Senior author Caroline Copeland expressed alarm at the presence of xylazine in the illicit drug market in the UK, warning that the drug poses a threat to a broader population beyond heroin users. She emphasized that unintentional exposure to xylazine, especially when combined with heroin, increases the risk of overdose.

Dangers Should Not Be Underestimated

Researchers identified xylazine in 16 individuals, with 11 cases resulting in fatalities. The report highlighted the challenges of detecting xylazine due to its short half-life, suggesting underestimation in drug-related fatalities.

In May 2023, King’s College London reported the first xylazine-related fatality in the UK, underscoring the growing concerns surrounding xylazine use. The combination of xylazine and fentanyl has been recognized as an emerging threat in the United States.

‘Skin-Rotting Zombie Drug’

Research from the Food and Drug Administration revealed that xylazine contributes to a significant percentage of drug overdoses in the US, with some states attributing up to 26% of all deaths to the drug.

Last year, US Senate Majority Leader Chuck Schumer described xylazine as a “skin-rotting zombie drug,” noting its deadly impact when mixed with other substances.

‘Public Health Threat’

The emergence of xylazine as a public health threat in the UK has raised concerns among researchers, urging the implementation of preventive measures to curb its proliferation. Recommendations include raising awareness among healthcare providers about the signs of xylazine use, conducting toxicology testing in relevant cases, and making affordable xylazine testing strips available.

In response to the growing threat, the government plans to classify xylazine as a Class C drug, imposing strict penalties for its supply to safeguard public health. Measures are being taken to combat the spread of xylazine and other synthetic drugs.

This report includes contributions from Chris Summers and PA Media.



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